Chitosan:xanthan:anionic collagen hydrogels. Formulation and characterization / Obtenção e caracterização de hidrogéis de quitosana, xantana e colágeno aniônico

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

Hydrogel are polymeric materials, which have the capacity to retain a great amount of water, and are often used as biomaterials. Chitosan, xanthan and collagen present biocompatibility and they can be used in tissue regeneration and drug delivery. In this work hydrogels were prepared by the mixture with chitosan (from β-quitina), commercial xanthan and anionic collagen (from bovine tendon) in different proportions. They were characterized by thermal analysis (thermogravimetry and differential scanning calorimetry), infrared spectroscopy (FTIR), scanning electronic microscopy and water absorption. Thermogravimetric curves showed that all hydrogels present a great amount of water and after the rehydratation were capable to keep the same amount of water. Melting point of water in DSC curves were shifted to higher values due the increase of water/polymer interaction. FT-IR showed characteristic bands of biopolymers with the absence of new bands and the morphology (MEV) showed that the hydrogels structures were in sheet form and the collagen fibers are visible in the hole structure.

ASSUNTO(S)

xanthan chitosan xantana quitosana hidrogel hydrogel

ACESSO AO ARTIGO

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