Chemical mapping of co-existing RNA structures.

AUTOR(ES)

Schröder, A R

RESUMO

In many cases RNA can assume co-existing or meta-stable structures preventing structure determination by chemical mapping. A novel method is described, by which RNA is modified with dimethyl sulphate without shifting the distribution of different structures. The different structures are then separated in native gel electrophoresis, and structure determination by primer extension can be carried out separately for each structure.

Documentos Relacionados

• Cardiology and Co-Existing Disease
• Co-existing conjunctival non-Hodgkin's lymphoma and pulmonary sarcoidosis.
• A rare case of breast carcinoma co-existing with axillary mantle cell lymphoma
• Spatial variation of five co-existing siluriformes in an atlantic rain forest drainage
• The Clinico-pathological Syndrome Produced by Co-existing Pulmonary Arterial and Venous Hypertension