Characterization of tumor cell lines derived from murine gammaherpesvirus-68-infected mice.
AUTOR(ES)
Usherwood, E J
RESUMO
Cell lines were derived from mice with murine gammaherpesvirus-68 (MHV-68)-associated lymphoproliferative disease. Four were of an ambiguous phenotype and were MHV-68 negative. One, S11, was a B lymphocyte that contained MHV-68 genomes in both linear and episomal forms and released virus. The line was clonable and grew into tumors in nude mice. This is the first naturally occurring MHV-68-positive B-cell line to be generated, and it will be an invaluable tool for the study of MHV-68 latency.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=190690Documentos Relacionados
- Turnover of T Cells in Murine Gammaherpesvirus 68-Infected Mice
- Characterization of Murine Gammaherpesvirus 68 Glycoprotein B
- Three Distinct Regions of the Murine Gammaherpesvirus 68 Genome Are Transcriptionally Active in Latently Infected Mice
- Variation in p30-related proteins in gross virus-induced tumor cell lines derived from H-2 congenic mice.
- Structure of retroviral RNAs produced by cell lines derived from spontaneous lymphomas of AKR mice.
