Characterization of a circular plasmid from Borrelia burgdorferi, etiologic agent of Lyme disease.
Hyde, F W
Borrelia burgdorferi, the etiologic agent of Lyme disease, was recently shown to contain plasmid DNA. Two plasmid species have been described in strain CT1, a Wisconsin tick isolate: a 9.2-kilobase entity; and a larger, 70-kilobase entity. Characterization of the 9.2-kilobase entity by using DNase I and restriction endonucleases demonstrated that the plasmid is supercoiled and exists as a stable dimer in this strain. The role played by the plasmid in B. burgdorferi is unknown.
ACESSO AO ARTIGOhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=266849
- Plasmid analysis of Borrelia burgdorferi, the Lyme disease agent.
- Detection of antigens in urine of mice and humans infected with Borrelia burgdorferi, etiologic agent of Lyme disease.
- Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease.
- Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirochete.
- Complete nucleotide sequence of a circular plasmid from the Lyme disease spirochete, Borrelia burgdorferi.