Central nervous system involvement in Hodgkin's lymphoma associated with Epstein-Barr virus in a patient with AIDS: case report and review of the literature

AUTOR(ES)

Corti, Marcelo, Fioti, María F. Villafañe, Yampolsky, Claudio, Schtirbu, Ricardo, Narbaitz, Marina

FONTE

Brazilian Journal of Infectious Diseases

DATA DE PUBLICAÇÃO

2006-12

RESUMO

Intracranial and intraspinal involvement is a rare complication of Hodgkin's disease. We report a case of a patient with diagnosis of AIDS and Hodgkin's lymphoma who developed brain and spinal involvement at the time of the relapse of the neoplasm disease. Mixed cellularity histology was the subtype of Hodgkin's disease in our patient; we identified the Epstein-Barr virus genome in the Reed-Sternberg cells by immunohistochemistry and in situ hybridization.

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