Catabolite repression of Escherichia coli heat-stable enterotoxin activity.
AUTOR(ES)
Martínez-Cadena, M G
RESUMO
The Escherichia coli heat-stable enterotoxin (ST) coded for by plasmid pYK007 (Apr ST+) showed a dependence for cyclic adenosine 3',5'-monophosphate (cAMP) to express ST activity in an adenyl cyclase (cya) deletion mutant; no ST activity was detected in the presence of cAMP in a cAMP receptor protein (crp) deletion mutant or in a double deletion mutant (delta cya delta crp). The cya-crp effect on ST activity could not be accounted for by a modification of the copy number of plasmid deoxyribonucleic acid per chromosome equivalent or by an alteration in the secretion of an active intracellular enterotoxin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=217171Documentos Relacionados
- Repression of heat-stable enterotoxin synthesis in enterotoxigenic Escherichia coli.
- Vascular permeability activity in Escherichia coli heat-stable enterotoxin.
- Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin.
- Heat-stable Escherichia coli enterotoxin production in vivo.
- Properties of synthetically produced Escherichia coli heat-stable enterotoxin.
