Case for diagnosis. A pruritic eruption of keratotic papules over the face and neck,
AUTOR(ES)
Relvas, Maria; Calvão, Joana; Coutinho, Inês; Cardoso, José Carlos
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2021-02
RESUMO
Abstract Generalized eruptive keratoacanthoma of Grzybowski is a rare variant of multiple keratoacanthomas counting with about 40 cases reported. It is a chronic and progressive disease for which none of the described therapeutic options has been entirely satisfactory. We report a case of an 83-year-old female who presented with a 3-month history of extremely pruritic, multiple, skin-coloured to erythematous to brownish, millimetric papules, with a keratotic centre. Histological examination of an incisional biopsy was consistent with the diagnosis of keratoacanthoma. The patient started acitretin 25 milligrams daily with a complete resolution of pruritus and regression of numerous lesions.
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