Cardiac Magnetic Resonance and amyloidosis: Review

AUTOR(ES)

Ribeiro, Vaneza Ferreira

FONTE

Int. J. Cardiovasc. Sci.

DATA DE PUBLICAÇÃO

2019-04

RESUMO

Abstract Amyloidosis is a disease caused by extracellular deposition of insoluble protein fibrils, that results in changes in tissue architecture and consequently modification of the organ structure. Cardiac involvement is common in amyloidosis. Two major types of systemic amyloidosis affect the myocardium - immunoglobulin light chain and transthyretin amyloidosis - each leading to different prognosis. Early detection and diagnosis of cardiac amyloidosis are the main objectives in the assessment of the disease. New techniques of magnetic resonance imaging have minimized the need for biopsies for the diagnosis. Late gadolinium enhancement technique, and more recently T1 mapping, have allowed a simplified evaluation of amyloid deposits and extracellular volume. The aim of this review was to describe basic concepts and updates of the use of magnetic resonance imaging for the diagnosis amyloidosis and evaluation of its severity.

Documentos Relacionados

• Primary Amyloidosis: A Review
• Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant.
• Cardiac amyloidosis: non-invasive diagnosis
• Familial and primary (AL) cardiac amyloidosis: echocardiographically similar diseases with distinctly different clinical outcomes.
• Clinical Profile of Patients with Head and Neck Amyloidosis: A Single-Institution Retrospective Chart Review