Can Pooling Be Used for Seroprevalence Studies of Hepatitis C?

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

Two hepatitis C antibody assays were used to test diluted positive sera. Dilutions of 1 in 5, 1 in 10, and 1 in 20 all resulted in loss of reactivity, with the greatest losses occurring in samples with low and moderate reactivities. These results disqualify pooling as a strategy for seroprevalence studies and screening programs.

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