Calcium phosphate-mediated transfection alters metallothionein gene expression in response to Cd2+ and Zn2+.
AUTOR(ES)
Foster, R
RESUMO
The level of expression of a transfected metallothionein (MT)-IGcat fusion gene in response to cadmium differed from that of the endogenous MT-IG gene. Atomic absorption analysis indicated that the total cellular content of cadmium and zinc increased upon calcium phosphate-mediated transfection. Thus, changes in the influx/efflux of metals may regulate the level of MT gene expression.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=362482Documentos Relacionados
- Alteration of the tumorigenic and metastatic properties of neoplastic cells is associated with the process of calcium phosphate-mediated DNA transfection.
- Dolichyl phosphate-mediated mannosyl transfer through liposomal membranes.
- Characterization of the Phosphate-mediated Control of Ethylene Production by Penicillium digitatum
- Phosphate-Mediated Alteration of the Microsporum gypseum Germination Protease Specificity for Substrate: Enhanced Keratinase Activity
- Determination of the binding sites of the proton transfer inhibitors Cd2+ and Zn2+ in bacterial reaction centers
