blaCTX-M-2 Is Located in an Unusual Class 1 Integron (In35) Which Includes Orf513

AUTOR(ES)

Arduino, Sonia M.

FONTE

American Society for Microbiology

RESUMO

Examination of the blaCTX-M-2 gene in plasmid pMAR-12 by sequencing and PCR analysis revealed that the bla gene and the surrounding DNA, which is closely related (99% homology) to the Kluyvera ascorbata chromosomal DNA that contains the blaKLUA-1 gene, are located in a complex sul1-type integron, termed In35, that includes Orf513. It is possible that blaCTX-M-2 was acquired by plasmid pMAR-12 through an uncharacterized recombinational event in which Orf513 could be involved.

Documentos Relacionados

• Novel Class 1 Integron (InS21) Carrying blaCTX-M-2 in Salmonella enterica Serovar Infantis
• blaCTX-M-2 and blaCTX-M-28 extended-spectrum β-lactamase genes and class 1 integrons in clinical isolates of Klebsiella pneumoniae from Brazil
• In34, a Complex In5 Family Class 1 Integron Containing orf513 and dfrA10
• Novel Complex sul1-Type Integron in Escherichia coli Carrying blaCTX-M-9
• ISEcp1B-Mediated Transposition of blaCTX-M in Escherichia coli