Beta Interferon Is Produced by Chlamydia trachomatis-Infected Fibroblast-Like Synoviocytes and Inhibits Gamma Interferon-Induced HLA-DR Expression
AUTOR(ES)
Rödel, Jürgen
FONTE
American Society for Microbiology
RESUMO
Infection of fibroblast-like synovial cells with Chlamydia trachomatis (serotype D strain IC Cal 8) in culture induced the secretion of beta interferon (IFN-β). Chlamydial infection inhibited IFN-γ-induced expression of HLA-DR antigen in the cells. Addition of IFN-β antibody directly to infected cultures mitigated HLA-DR inhibition, suggesting involvement of produced IFN-β.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=108543Documentos Relacionados
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