Beneficial effects of botulinum toxin type A in trigeminal neuralgia

AUTOR(ES)

Zúñiga, Carlos, Díaz, Sergio, Piedimonte, Fabián, Micheli, Federico

FONTE

Arquivos de Neuro-Psiquiatria

DATA DE PUBLICAÇÃO

2008-09

RESUMO

Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were also infiltrated in the masseter muscle. The patients were assessed on a weekly basis using the Visual Analogic Scale for pain. Ten of our patients reported a significant benefit from botulinum toxin injections, with reduction or even disappearance of pain, and remained pain free for as long as 60 days. Our findings suggest that botulinum toxin may represent a useful therapeutic tool in the management of patients with this entity.

Documentos Relacionados

• Effects of acrylamide and botulinum toxin on horseradish peroxidase labelling of trigeminal motor neurons in the rat.
• Controlled thermocoagulation in trigeminal neuralgia.
• Trigeminal neuralgia in pontine ischaemia.
• Clinical manual of trigeminal neuralgia
• Molecular Weight of Type A Botulinum Toxin