Bafilomycin A1 and intracellular multiplication of Legionella pneumophila.
AUTOR(ES)
Cattani, L
RESUMO
Multiplication of Legionella pneumophila in HeLa cells was found to be inhibited by noncytotoxic concentrations of bafilomycin A1, with blockage of bacterial growth at a concentration 15.6 nM. The inhibiting action was evident only when the antibiotic was present during the initial phase of intracellular multiplication, i.e., during the formation of the phagosome, whereas the addition of the drug did not affect microorganisms already actively multiplying within the phagosome.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=163689Documentos Relacionados
- Isolation of protozoa from water associated with a legionellosis outbreak and demonstration of intracellular multiplication of Legionella pneumophila.
- Association of flagellum expression and intracellular growth of Legionella pneumophila.
- A plasmid in Legionella pneumophila.
- Cytotoxicity of extracellular Legionella pneumophila.
- Ecological distribution of Legionella pneumophila.