Bacterial Production of d-Erythroascorbic Acid and l-Ascorbic Acid through Functional Expression of Saccharomyces cerevisiae d-Arabinono-1,4-Lactone Oxidase in Escherichia coli
AUTOR(ES)
Lee, Byung-Hoon
FONTE
American Society for Microbiology
RESUMO
d-Arabinono-1,4-lactone oxidase, which catalyzes the terminal step in the biosynthesis of d-erythroascorbic acid in Saccharomyces cerevisiae, was functionally expressed in Escherichia coli inherently lacking the enzyme. The recombinant E. coli strain expressing the enzyme could overproduce d-erythroascorbic acid and l-ascorbic acid when supplied with d-arabinono-1,4-lactone and l-galactono-1,4-lactone, respectively.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=91626Documentos Relacionados
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