Avaliação do refluxo gastroesofagico em criancas e adolescentes asmaticos atopicos graves com e sem pneumonias recidivantes

AUTOR(ES)
DATA DE PUBLICAÇÃO

1999

RESUMO

An assessment of gastroesophageal reflux in children and adolescents with severe atopic asthma with and without recurrent pneumonia In order to evaluate the role of gastroesophageal reflux (GER) as a possible cause of recurrent pneumonia (RP) in children and adolescents with severe atopic asthma (AA), 44 patients were studied prospectively with prolonged (24hour) esophageal pH-monitoring. Their ages ranged from ? to 15 years. There were no significant differences detected between group 1 (AA without RP) and group 2 (AA with RP) when sex, age, maternal or paternal smoking, atopic status, and lung function tests were evaluated. The prevalence of GER was 31,6% (6/19) in group 1 and 48% (12/25) in group 2. The following parameters were evaluated: mean percentage of time pH<4, the number of GER episodes/hr, esophageal clearance and the longest reflux episode. Esophageal acid exposme (mean percentage of time with pH<4) (p= 0,00245) and the number of GER episodes/hr (p=0,0091) in supine position were significantly increased in group 2 as compared to group 1. Furtherrnore, group 2 shows higher values of !lUmber of GER episodes/hour (p=0,043). Thus, our results show that patients with AA and RP differ from AA without RP by the characteristics of their refluxo We therefore, suggest to perforrn prolonged esophageal monitoring as a standard procedure in asthmatic patients with RP

ASSUNTO(S)

pneumonia asma em crianças refluxo gastroesofagico

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