Asymmetric Dimethylarginine and Mortality in Stages 3 to 4 Chronic Kidney Disease

AUTOR(ES)
FONTE

American Society of Nephrology

RESUMO

Background and objectives: Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, reduces bioavailability of nitric oxide and induces endothelial dysfunction. This dimethylated amino acid accumulates in chronic kidney disease and may be involved in the pathophysiology of cardiovascular disease (CVD) in this population.

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