Assessment of the body burden of chelatable lead: a model and its application to lead workers.
AUTOR(ES)
Araki, S
RESUMO
A hypothetical model was introduced to estimate the body burden of chelatable lead from the mobilisation yield of lead by calcium disodium ethylenediamine tetra-acetate (CaEDTA). It was estimated that, on average, 14 and 19% of the body burden was mobilised into the urine during the 24 hours after an injection of 53.4 mumol (20 mg) and 107 mumol (40 mg) CaEDTA per kg bodyweight, respectively. The body burden of chelatable lead ranged from 4 mumol (0.8 mg) to 120 mumol (24.9 mg) (mean 37 mumol (7.7 mg) in lead workers with blood lead concentrations of 0.3-2.9 mumol/kg (6-60 microgram/100 g) (mean 1.4 mumol/kg (29 microgram/100 g)). There were linear relationships between blood lead concentrations and body burden of chelatable lead on a log scale.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1008963Documentos Relacionados
- Comparison of measures of lead exposure, dose, and chelatable lead burden after provocative chelation in organolead workers.
- Urinary non-precipitable lead in lead workers.
- Cognitive functioning in lead workers.
- Lead poisoning in a group of demolition workers.
- A longitudinal study of the relation of lead in blood to lead in air concentrations among battery workers.