Arsenic exposure and mortality: a case-referent study from a Swedish copper smelter.
AUTOR(ES)
Axelson, O
RESUMO
An increased mortality from lung cancer, cardiovascular disease, haematolymphatic malignancy and cirrhosis of the liver has been reported among smelter workers and others exposed to arsenic. This study uses the case-referent (case-control) technique and is concerned with workers in a copper smelter in a complex work environment, characterised by the presence of trivalent arsenic in combination with sulphur dioxide and copper, and also with other agents. Lung cancer mortality was found to be increased about five-fold and cardiovascular disease about two-fold, showing a dose-response relationship to arsenic exposure. Mortality from malignant blood disease (leukaemia and myeloma) and cirrhosis of the liver was also slightly increased. This mortality pattern among the smelter workers is consistent with earlier reports. An increased mortality from cardiovascular disease in this type of industry is of particular interest as it has been reported only once before.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1008317Documentos Relacionados
- Diabetes mellitus and arsenic exposure: a second look at case-control data from a Swedish copper smelter.
- Dust exposure in coeliac disease: a case-referent study.
- Radiological irregular opacities and coalwork exposure: a case-referent study.
- Chronic glomerulonephritis and exposure to solvents: a case-referent study.
- Occupational exposure to hydrocarbons and chronic pancreatitis: a case-referent study.