Arginase: marker, effector, or candidate gene for asthma?

AUTOR(ES)

Vercelli, Donata

FONTE

American Society for Clinical Investigation

RESUMO

Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression, suggesting that arginine pathways are critical in the pathogenesis of asthma.

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