Aplicações sintéticas do ácido mucobrômico e da 3,4-dibromofuran-2(5H)-ona

AUTOR(ES)

Cunha, Silvio, Oliveira, Caio C.

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2011

RESUMO

This review describes the use of two biomass-derivate butenolides as intermediates in organic synthesis, mucobromic acid and its reduced derivative 3,4-dibromofuran-2(5H)-one. The ambiphilic and ambident character of such butenolides make them versatile starting materials in the synthesis of natural and/or bioactive compounds. Thus, the reactions of mucobromic acid with C-nucleophiles and heteronucleophiles are described, as well as the nucleophilic addition to carbonyl reactions of 3,4-dibromofuran-2(5H)-one. Besides, both compounds are active in diverse metal cross-coupling reactions, manly with palladium in Suzuki and Sonogashira reactions.

Documentos Relacionados

• Synthesis of 3-bromotetronamides via amination of 3,4-dibromofuran-2(5H)-one
• Estudo da atividade citotóxica do poliacetileno 5-octa-2, 4, 6-triinil-furan-2(5H)-ona
• PERFIL FARMACOLÓGICO DO TIPO ANTIDEPRESSIVO DO COMPOSTO 3-(4-FLUOROFENILSELENIL)-2,5 DIFENILSELENOFENO: ENVOLVIMENTO DO SISTEMA SEROTONINÉRGICO
• Reações de 2-alcóxi-5-trifluoracetil-3,4-diidro-2H-piranos com etilaminas substituídas e arilaminas
• Synthesis of 2-[5-Aryl-3-(E-styr-1-yl)-4,5-Dihydro-1H-pyrazol-1-yl]-4-Phenyl-6-Trifluoromethylpyrimidines