Antioxidant capacity of eugenol derivatives

AUTOR(ES)

Hidalgo, María E., De la Rosa, Carlos, Carrasco, Héctor, Cardona, Wilson, Gallardo, Claudio, Espinoza, Luis

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2009

RESUMO

Toxicity and antioxidant capacity of eugenol derivatives (E2 = 2-Methoxy-4-[1-propenylphenyl]acetate, E3 = 4-Allyl-2-methoxyphenylacetate, E4 = 4-Allyl-2-methoxy-4-nitrophenol, E5 = 5-Allyl-3-nitrobenzene-1,2-diol, E6 = 4-Allyl-2-methoxy-5-nitrophenyl acetate) were evaluated in order to determine the influence of the sustituents. E2-E6 were synthesized from eugenol (E1). E1 was extracted from cloves oil, and E2-E6 were obtained through acetylation and nitration reactions. Antioxidant capacity evaluated by DPPH (1, 1-Diphenyl-2-picrylhydrazil) and ORAC fluorescein demonstrated that E1 and E5 have a higher capacity and the minor toxicity evaluated by red blood cells haemolysis and the Artemia saline test. In accordance with our results, the compound's (E1-E5) use in the pharmaceutical, cosmetic and or food industries could be suggested.

Documentos Relacionados

• Synthesis of Eugenol-Fluorinated Triazole Derivatives and Evaluation of Their Fungicidal Activity
• Changes in composition, antioxidant content, and antioxidant capacity of coffee pulp during the ensiling process
• Analysis of the Total Antioxidant Capacity of Saliva in Smokers
• MAXIMIZATION OF ESSENTIAL OIL ANTIOXIDANT CAPACITY VIA STAR ANISE HYDRODISTILLATION
• Total and corrected antioxidant capacity in hemodialyzed patients