Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae)

AUTOR(ES)

Costa, Emmanoel Vilaça, Pinheiro, Maria Lúcia Belém, Silva, Jefferson Rocha de Andrade, Maia, Beatriz Helena Lameiro de Noronha Sales, Duarte, Marta Cristina Teixeira, Amaral, Ana Cláudia Fernandes, Machado, Gérzia Maria de Carvalho, Leon, Leonor Laura

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2009

RESUMO

bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.

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