Antimicrobial activity of wax and hexane extracts from Citrus spp. peels
Johann, Susana, Oliveira, Vetúria Lopes de, Pizzolatti, Moacir G, Schripsema, Jan, Braz-Filho, Raimundo, Branco, Alexsandro, Smânia Jr, Artur
Memórias do Instituto Oswaldo Cruz
DATA DE PUBLICAÇÃO
Antibacterial and antifungal properties of wax and hexane extracts of Citrus spp. peels were tested using bioautographic and microdilution techniques against three plant pathogenic fungi (Penicillium digitatum, Curvularia sp., and Colletotrichum sp.), two human pathogens (Trichophyton mentagrophytes and Microsporum canis), and two opportunistic bacteria (Escherichia coli and Staphylococcus aureus). Two polymethoxylated flavonoids and a coumarin derivative, were isolated and identified from peel extracts, which presented antimicrobial activity especially against M. canis and T. mentagrophytes: 4',5,6,7,8-pentamethoxyflavone (tangeritin) and 3',4',5,6,7,8-hexamethoxyflavone (nobiletin) from C. reticulata; and 6,7-dimethoxycoumarin (also known as escoparone, scoparone or scoparin) from C. limon.
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