Angiotensin-I-converting enzyme and its relatives

AUTOR(ES)
FONTE

BioMed Central

RESUMO

Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc- and chloride-dependent protein that catalyzes the conversion of the decapeptide angiotensin I to the octapeptide angiotensin II. ACE is a key part of the system that regulates blood pressure, and recent X-ray structures may help design improved ACE inhibitors.

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