Angiogenesis in a Patient with Ischemic Limb: Induced by Intramuscular Injection of Vascular Endothelial Growth Factor and Fibrin Platform

AUTOR(ES)

Kipshidze, Nicholas

RESUMO

Direct revascularization of critical ischemia of the limb is often unsuccessful due to the anatomic extent and distribution of arterial occlusive disease, and no pharmacologic treatment has proved effective in treating this condition. Patients with ischemic limb may eventually require amputation and may develop serious morbidity and mortality. The goal of limb salvage in these patients has stimulated research into alternative treatment methods, including angiogenesis.

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