Analise quantitativa, duração do ciclo do epitelio seminifero e produção espermatica do testiculo do gerbilo da Mongolia (Meriones unguiculatus)

AUTOR(ES)
DATA DE PUBLICAÇÃO

2003

RESUMO

The gerbil (Meriones unguiculatus) is a rodent native of the arid regions of Mongolia and China, is of special interest in biomedical research and has been bred in laboratory since 1960. Studies on the structure and function of the gerbil testis are sporadic and, moreover those on spermatogenesis are rare. This is the first study to perform a more detailed investigation about duration of the spermatogenic cycle and morphometric and functional analysis of the gerbil testis. Through 3H-thymidine injection tecnic, the mean duration of seminiferous epithelium cyc1e was determined to be 10.55 :t 1.0 days and the total duration of spermatogenesis based on 4.5 cyc1es was 47.47 days. The volume density of tubular and interstitial compartments was approximately 92% and 8%, respectively. Based on the volume of the testis parenchyma and the volume occupied by seminiferous tubules in the testis and the tubular diameter, about 9 and 18 meters of seminiferous tubules were found per testis and per gram of testis, respectively. About 12 primary spermatocytes were formed for each type A1 spermatogonia. The meiotic index was 2.8. This result shows that 30% of cell loss occurs during the two meiotic divisions. The number of Sertoli cell per gram of the testis was 28 million and the supporting capacity was 21 germ cel1. The daily sperm production per gram of the testis was 33 million. This value suggest high spermatogenic efficiency in this specie. The gerbil could be utilized as an animal model for future investigation of spermatogenic process

ASSUNTO(S)

testiculos espermatogenese celulas de celulas germinativas sertoli

ACESSO AO ARTIGO

Documentos Relacionados