Análise morfométrica 2D e 3D de amostras de osso trabecular utilizando microtomografia tridimensional por raio-X / 2D and 3D morphometric analysis of trabecular bone using X-ray tridimensional microtomography (müCT)

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Trebecular bones have a porous microstructure and can be modeled as a linear elastic solid, heterogenous and anisotropic. The x-ray tridimensional microtomography (müCT) has been worldwide used for the assessment of trabecular bone in investigations related to bone quality and aimed to the diagnostic of bone metabolic diseases such as osteoporosis. In the literature few investigations have compared the 2D and 3D morphometric analysis of trabecular bone. In this investigation cylindrical trabecular bone samples were harvested from bovine head femur to carry out that comparison by müCT. The CT-Analyser software was used to measure in three directions (superior-inferior, lateral-medial and anterior-posterior) several microstructural trabecular parameters such as trabecular thickness, trabecular separation, trabecular number and the eigenvalues of the fabric tensor (M). The comparison between the parameters values measured by 2D and 3D morphometric analysis was performed by the paired-sample t test with a level of significance p <0,05 and the Pearsons linear correlation. The eigenvalues show that the bovine trabecular microstructure has a tendence to transverse isotropy symmetry. The results show that x-ray tridimensional microtomography (müCT) is a technique of great potential for characterization of generating good bone quality parameters for the diagnosis of diseases of bone metabolism.

ASSUNTO(S)

tensor anisotropia fabric tensor osso trabecular análise morfométrica 2d e 3d 3d x-ray microtomography ( mü ct) microtomografia tridimensional ( mü ct) trabecular bone 2d and 3d morphometric analysis bone quality qualidade óssea

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