Analise microbiologica e suscetibilidade antimicrobiana de alguns microrganismos isolados de canais radiculares infectados associados a lesões periapicais

AUTOR(ES)
DATA DE PUBLICAÇÃO

2003

RESUMO

The aim of this study was to analyse the microflora isolated ITom infected root canals of symptomatic or asymptomatic teeth, to correlate the presence of specific bacteria with endodontic symptomatology and to investigate the antibiotic susceptibility of the anaerobic Gram-negative bacteria isolated ITom symptomatic teeth with periapicallesions against 8 antibiotics through the E-test. Microbial samples were taken ITom root canals of 48 teeth with necrotic dental pulp, 29 symptomatic and 19 asymptomatic, using adequate techniques. A total of 218 cultivable isolates were recovered ITom 48 different microbial species and 19 different genera. Root canals ITom symptomatic teeth harboured more obligate anaerobes and a bigger number of bacterial species than the asymptomatic teeth. More than 70% ofthe total bacterial isolates were strict anaerobes. Statistical analysis used a Pearson r test or a one-sided Fisher s Exact test, as appropriate. Relationships were found between specific microorganisms, especially Gram-negative anaerobes and the presence of pain or histol) ofpain, tendemess to percussion, pain to palpation and swelling. Amoxicillin, amoxicillin + clavulanate and cephaclor were efIective against all the strains tested. The lowest susceptibility rate was presented by Prevotella intermedia/nigrescens against penicillin G. Our results suggested that specific bacteria are associated with endodontic symptoms of infected teeth and the majority of the Gram-negative bacterial species tested were susceptible to all antibiotics studied

ASSUNTO(S)

microorganismos antibioticos endodontia

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