An unappreciated role for RNA surveillance

AUTOR(ES)

Hillman, R Tyler

FONTE

BioMed Central

RESUMO

Following the hypothesis that the public databases contain cloned mRNAs that would be degraded in vivo by the nonsense-mediated mRNA decay mechanism, 144 isoform sequences deposited in SWISS-PROT have been identified that derive from mRNAs with premature termination codons

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