An effect of castration and testosterone replacement on a circadian pacemaker in mice (Mus musculus).

AUTOR(ES)

Daan, S

RESUMO

Castration of mice in freerunning conditions (total darkness, DD) causes a reduction of running wheel activity in the beginning of the active period (alpha) and stimulates activity at the end of alpha. Simultaneously, the period (tau) of the freerunning rhythm is increased. Both effects are abolished by implantation of a Silastic capsule from which a physiological dose of testosterone is released at a constant rate. The results are tentatively explained by differential endocrine influences on two oscillating components in the pacemaker of the circadian activity rhythm.

Documentos Relacionados

• SEM analysis of body hairs and whiskers of heterozygous tortoiseshell (Moto/+) female mice (Mus musculus).
• The effect of the gene undulated (un) on the shape of cervical and upper thoracic vertebrae in the house mouse (Mus musculus).
• Transcripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus).
• Two Radiation-Induced Chromosomal Inversions in Mice (Mus musculus)
• Hematology of Swiss mice (Mus musculus) of both genders and different ages