Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital

AUTOR(ES)

Saavedra, Pamela Alejandra, Meiners, Micheline Marie Milward de Azevedo, Lopes, Luciane Cruz, Silva, Emília Vitória da, Silva, Dayde Lane Mendonça da, Noronha, Elza Ferreira, Toledo, Maria Inês de

FONTE

Rev. Soc. Bras. Med. Trop.

DATA DE PUBLICAÇÃO

2016-12

RESUMO

Abstract INTRODUCTION: Despite the therapeutic benefits of drugs, adverse drug reactions (ADRs) occur. Method: We assessed a series of suspected ADRs identified from notifications and intensive monitoring of inpatients from March 2013 to March 2014. RESULTS: Skin reactions predominated (31%). Systemic anti-infective agents were implicated in 16 (72%) reactions. Fifteen (68%) ADRs were classified as possible. The implicated drug was not correctly identified by the healthcare team in 12 cases. CONCLUSIONS: Some reactions were not correctly attributed to the causative drug(s), suggesting that the use of a validated evaluation method can promote successful identification of causal links between ADRs and drugs.

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