Adenomatous Human Parathyroid Cells Exhibit Impaired Sensitivity to l-Amino Acids
AUTOR(ES)
Mun, H.-C.
FONTE
The Endocrine Society
RESUMO
Context: Primary hyperparathyroidism, which occurs most commonly in patients with adenomatous disease of a single parathyroid gland, arises as a result of impaired extracellular Ca2+ (Ca2+o)-dependent feedback on PTH secretion, a process mediated by the calcium-sensing receptor (CaR).
