Adaptation of an osmotically fragile L-form of Streptococcus pyogenes to physiological osmotic conditions and its ability to destroy human heart cells in tissue culture.
AUTOR(ES)
Leon, O
RESUMO
An osmotically fragile L-form of Streptococcus pyogenes, type 12, was quickly rendered osmotically stable by decreasing the sodium chloride content of the growth medium and with the temporary use of oleic acid. The change from osmotic fragility to stability was accompanied by changes in cell yield, generation time, saturated/unsaturated fatty acid ratio of the membrane, and cytoplasmic protein composition. Finally, this resulting osmotically stable L-form survived and was capable of rapidly destroying Girardi human heart cells in tissue culture.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=420602Documentos Relacionados
- Effect of L-form Streptococcus pyogenes and of lipoteichoic acid on human cells in tissue culture.
- Persistence, pathogenesis, and morphology of an L-form of Streptococcus pyogenes adapted to physiological isotonic conditions when in immunosuppressed mice.
- Transport of α-Aminoisobutyric Acid by Streptococcus pyogenes and Its Derived L-Form
- Teichoic Acid of a Stabilized L-Form of Streptococcus pyogenes
- Incorporation of d-Alanine into the Membrane of Streptococcus pyogenes and Its Stabilized L-Form
