Active compounds and derivatives of camellia sinensis responding to erosive attacks on dentin
AUTOR(ES)
Passos, Vanara Florêncio, Melo, Mary Anne Sampaio de, Lima, Juliana Paiva Marques, Marçal, Felipe Franco, Costa, Cecília Atem Gonçalves de Araújo, Rodrigues, Lidiany Karla Azevedo, Santiago, Sérgio Lima
FONTE
Braz. oral res.
DATA DE PUBLICAÇÃO
24/05/2018
RESUMO
Abstract This research explored the potential of Camellia sinensis-derived teas and active compounds to be used as treatments to prevent dentin wear. Human root dentin slabs were randomly assigned to 5 groups (n = 10) as follows: distilled water (DW, control), epigallocatechin-3-gallate (EGCG), theaflavin gallate derivatives (TF), commercial green tea (GT), and commercial black tea (BT). The samples were submitted to a pellicle formation and an erosive cycling model (5x/day, demineralization using 0.01 M hydrochloric acid/60 s) followed by remineralization (human stimulated saliva/60 min) for three days. The samples were treated for 5 min using the test group solutions between the erosive cycles. Dentin changes were assessed with profilometry analysis and FT-Raman spectroscopy. The data regarding wear were analyzed by ANOVA followed by Tukey's test (p < 0.05). EGCG, TF derivatives, and both regular teas significantly suppressed erosive dentin loss (38–47%, p < 0.05). No obvious changes in the Raman spectra were detected in the specimens; however, the DW group had a minor relationship of 2880/2940 cm−1. The phenolic contents in both green and black tea and the important catechins appear to have protective effects on dentin loss.
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