Activation of serum 5′ nucleotidase by magnesium ions and its diagnostic applications
AUTOR(ES)
Belfield, A.
RESUMO
Magnesium ions increase the hydrolysis of adenosine 5′ monophosphate (5′ AMP) by human serum at pH 7·9 but not at pH 9·3. The additional hydrolysis at pH 7·9 is predominantly due to increased activity of the specific phosphatase 5′ nucleotidase (5Nase). This increase is proportional to enzyme concentration and has been employed as a measure of 5Nase activity in a sensitive micro-estimation.
ACESSO AO ARTIGO
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