Acellular Pertussis Vaccines and Complement Killing of Bordetella pertussis

AUTOR(ES)

Weiss, Alison A.

FONTE

American Society for Microbiology

RESUMO

Antibody-dependent complement killing of Bordetella pertussis after immunization with a three-component acellular pertussis vaccine was characterized. Postimmunization activity was unchanged for about half of the adult vaccine recipients. The responses of the other individuals were complex, with evidence of both beneficial and antagonistic responses occurring, sometimes in the same individual.

Documentos Relacionados

• Bordetella pertussis Acquires Resistance to Complement-Mediated Killing In Vivo
• Characterization of Bactericidal Immune Responses following Vaccination with Acellular Pertussis Vaccines in Adults
• Growth Phase Influences Complement Resistance of Bordetella pertussis
• T-Cell Immune Response Assessment as a Complement to Serology and Intranasal Protection Assays in Determining the Protective Immunity Induced by Acellular Pertussis Vaccines in Mice
• Evaluation of respiratory model employing conventional NIH mice to access the immunity induced by cellular and acellular pertussis vaccines