Abacavir-induced liver toxicity

AUTOR(ES)

Pezzani, Maria Diletta, Resnati, Chiara, Di Cristo, Valentina, Riva, Agostino, Gervasoni, Cristina

FONTE

Braz J Infect Dis

DATA DE PUBLICAÇÃO

2016-10

RESUMO

Abstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.

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