A NEW SECO-LIMONOID FROM THE INFLORESCENCES OF Dictyoloma vandellianum

AUTOR(ES)

Pereira, Laiane Caline Oliveira; Abreu, Lucas Silva; Silveira, Mayra Bitencourt; Nascimento, Yuri Mangueira do; Souza, Thalisson Amorim de; Hyaric, Mireille Le; Lisboa, Thaís Mangeon Honorato; Sobral, Marianna Vieira; Velozo, Eudes da Silva; Tavares, Josean Fechine; Silva, Marcelo Sobral da

FONTE

Quím. Nova

DATA DE PUBLICAÇÃO

2020-05

RESUMO

Phytochemical investigation of the inflorescences of Dictyoloma vandellianum A. Juss. (Rutaceae) has led to the isolation of a new A-seco-limonoid, named dictyolomol (1), along with a known quinolone alkaloid, casimiroine (2), previously isolated from the same species. The structures were established by spectroscopic analysis such as one- and two-dimensional NMR, IR, high-resolution mass spectrometry and chemical transformations. The isolated compounds (1 and 2) and O-acetyl derivative (1a) were evaluated for their cytotoxicity against MCF-7 and HeLa cancer cell lines. The results indicated that 1, 1a and 2 showed no significant cytotoxicity.

Documentos Relacionados

• New Limonoids from Dictyoloma vandellianum and Sohnreyia excelsa: Chemosystematic Considerations
• Morfologia e anatomia da semente de Dictyoloma vandellianum Adr. Juss.(Rutaceae)
• Nutritional value of banana inflorescences, study about transfer mechanisms of iron across the placenta, and new cytogenetic studies of Lippia (Verbenaceae) species from Brazil
• Anatomical and histochemical studies of the somatic embryogenesis of Syagrus oleracea from immature inflorescences
• Evaluation of limonoid production in suspension cell culture of Citrus sinensis