A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome.
AUTOR(ES)
Fang, Z
RESUMO
A 267-nucleotide Mycobacterium tuberculosis genomic sequence (ipl, the IS6110 preferential locus) which can harbor the insertion sequence IS6110 at six alternative locations has been identified in some three-quarters of the isolates tested. Only one IS6110 copy was observed at this locus in the ipl::IS6110(+)-containing isolates tested, and all insertions had the same orientation. The implications of this finding for IS6110 fingerprint typing methods is discussed in this work.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=229605Documentos Relacionados
- Phospholipase Region of Mycobacterium tuberculosis Is a Preferential Locus for IS6110 Transposition
- Reverse Dot Blot Assay (Insertion Site Typing) for Precise Detection of Sites of IS6110 Insertion in the Mycobacterium tuberculosis Genome
- IS6110 Insertions in Mycobacterium tuberculosis: Predominantly into Coding Regions
- Mapping of IS6110 Insertion Sites in Two Epidemic Strains of Mycobacterium tuberculosis
- Heminested inverse PCR for IS6110 fingerprinting of Mycobacterium tuberculosis strains.
