A Lipid-Peptide Microbicide Inactivates Herpes Simplex Virus
AUTOR(ES)
Isaacs, Charles E.
FONTE
American Society for Microbiology
RESUMO
A microbicide combining the lipid-ether 1-0-octyl-sn-glycerol (OG; 3 mM) and peptide D2A21 (9 μM) reduced herpes simplex virus type 1 (HSV-1) and HSV-2 titers by at least 1,000-fold, more than the sum of the inactivations produced by OG and D2A21 alone. OG plus D2A21 reduced HSV-1 and HSV-2 titers by ≥1,000-fold in ≤10 and ≤20 min, respectively, whereas OG and D2A21 used alone produced almost no virus inactivation during these times.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=478527Documentos Relacionados
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