A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

AUTOR(ES)
FONTE

Cold Spring Harbor Laboratory Press

RESUMO

We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.

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