A burst of c-fos gene expression in the mouse occurs at birth.
AUTOR(ES)
Kasik, J W
RESUMO
Expression of the c-fos gene during murine perinatal development was studied. Before birth, all eight of the prenatal organs tested expressed undetectable or low levels of c-fos mRNA. On the day of birth, there occurred a 10- to 100-fold increase in the level of c-fos message in all of these organs. The expression was transient, in that 1 day after birth, the level of c-fos mRNA precipitously dropped. The c-fos gene expression at birth is unrelated to the expression of the c-myc gene and major histocompatibility complex class I genes, which display distinct kinetics during the perinatal development. The c-fos gene was also expressed locally and transiently in the gravid uterus 1 to 2 days prior to delivery. These results indicate that an event associated with birth induced c-fos gene expression in the mother and newborn.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=367977Documentos Relacionados
- Beta-adrenergic stimulation of c-fos gene expression in the mouse submandibular gland.
- c-fos proto-oncogene expression in the nervous system during mouse development.
- Serum stimulation of the c-fos enhancer induces reversible changes in c-fos chromatin structure.
- Transcriptional and posttranscriptional control of c-fos gene expression in human monocytes.
- Posttranscriptional regulation of c-fos mRNA expression.