ítulo em inglês: Analysis of respiratory rate and tidal volume as predictive of failure in very low birth weight infants / Análise da freqüência respiratória e do volume corrente como preditivo para a falha na extubação da recém-nascidos muito baixo peso.

AUTOR(ES)
DATA DE PUBLICAÇÃO

2006

RESUMO

Objetive: to analyze the relation between respiratory rate (RR) and tidal volume (TV) ratio as a predictive index for extubation very low birth weight infants submitted to mechanical ventilation. Methods: Prospective observational collection of data with newborns less than 37 weeks gestation, less than or iqual to 1.500 grams who were mechanically ventilated for at least 48 hours and less than 30 days and had planned extubation. As soon as physicians decided to extubate infant, a fixed-area pneumotachograph was installed between endotracheal tube and ventilator circuit. Infant stayed in endotracheal continuous positive airway pressure (CPAP) mode during 10 minutes and spontaneous tidal volume (TV) and respiratory rate (RR) were collected. After measurements, neonate was extubated and used nasal CPAP. Extubation failure was considered if infant required reintubation within 48 hours, except if infant evaluated with airway obstruction. RR/TV was indexed to body weight in the day of the study and means of RR, TV and RR/TV during 10 minutes were calculeted. For continuous variables were used Student t-test and for categorical variables between groups were used Chi-square or the Fishers exact test. A cutoff was calculated for respiratory rate and tidal volume and sensibility and specificity were also calculated. Results: Thirty-five infants were enrolled and fifteen (43%) failure extubation. During 10- minute measurements, there were no differences between groups in RR, TV and RR/TV. Specificity and sensibility were for RR 40% ,67%, TV was 50%, 67% and RR/TV was 40%, 73%, respectively. Conclusion: Respiratory rate tidal volume ratio was not a good predictor for extubation success.

ASSUNTO(S)

pneumologia premature,.mechanical ventilation, predictor, extubation, weaning 1. recém-nascidos 2. extubação 3. preditivo 4.desmame 5.ventilação mecânica

ACESSO AO ARTIGO

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