Apolipoprotein B
Mostrando 25-36 de 439 artigos, teses e dissertações.
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25. OXIMES AS INHIBITORS OF LOW DENSITY LIPOPROTEIN OXIDATION / OXIMAS COMO INIBIDORES DA OXIDAÇÃO DE LIPOPROTEÍNAS DE BAIXA DENSIDADE
The oxidation of low density lipoprotein is now an established hypothesis of atherogenesis and suggests that accumulation of oxidized low density lipoprotein (oxLDL) in the vessel wall is an early event in disease progression. OxLDL represents a variety of modification of both lipid and apolipoprotein B (apoB) components by peroxidation. This promotes athero
Publicado em: 2009
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26. Proteomic analisys of bovine yolk sac / Análise proteômica do saco vitelino de bovinos
The yolk sac plays an important role in embryonic development of all mammals. Its function is being studied, proving to be one of the initials of haematopoiesis. In the period when the placenta is not real yet formed during embryonic development, the yolk sac is the main source of nutrition of the embryo, providing a place for the transfer and synthesis of p
Publicado em: 2009
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27. Avaliação da hiperhomocisteinemia leve na evolução da aterosclerose em camundongos normais, com hemofilia B, deficiencia dos receptores para LDL ou da apolipoproteina E / Evaluation of mild hyperhomocysteinemia in the development of atherosclerosis in normal, hemophiliac B, LDL receptor-deficient or apolipoprotein E-deficient mice
This study evaluated the effect of controlled mild hyperhomocysteinemia (HHcy) in the development of atherosclerosis using normal, apolipoprotein E-deficient (apoE-/-), LDL receptor-deficient (LDLR-/-), or hemophilia B mice. We quantified atherosclerotic lesions at the aortic sinus and analyzed endoplasmic reticulum (RE) stress by western-blot technique. Con
Publicado em: 2008
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28. Modifications of the composition of plasma lipoproteins in physically trained young male individuals / Modificações da composição quimica de lipoproteinas plasmaticas em jovens do sexo masculino fisicamente exercitados
Regular physical activity is related to a reduced risk of cardiovascular disease possibly by improvement of the lipoprotein profile. But there are many deficiencies in the current knowledge in this area like at what age this benefit initiate, what is the amount and intensity of the exercises, among others. In this study we evaluated the efficiency of regular
Publicado em: 2008
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29. Chylomicron metabolism and lipid reception capacity of high density lipoprotein in metabolic syndrome (MetS) and type 2 diabetes mellitus (DM2) / Metabolismo dos quilomícrons e capacidade da lipoproteína de alta densidade (HDL) de receber lípides na síndrome metabólica e no diabetes mellitus tipo 2
The main metabolic disturbances occurring as a result of type 2 diabetes mellitus (DM2) and Metabolic Syndrome (MetS) are alterations in the metabolism of lipids. It is therefore, important to better understand the aspects by which plasma lipoproteins are metabolized. The evaluation of chylomicron metabolism and lipid transfer of high density lipoprotein (HD
Publicado em: 2008
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30. Correlation between hypermutation and viral load in patients infected with human immunodeficiency virus type 1 (HIV-1) / Análise de correlação entre eventos de hipermutação e carga viral em pacientes infectados pelo vírus da imunodeficiência humana tipo 1(HIV-1).
INTRODUÇÃO: A substituição monótona de bases G → A no genoma do HIV-1 é observada desde a década de 1990, entretanto, apenas recentemente esse efeito foi atribuído às APOBECs (apolipoprotein B editing catalytic polypeptide) da imunidade inata. As APOBECs celulares atuam na deaminação de citidina a uridina na fita de DNA viral de polaridade n
Publicado em: 2008
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31. Purification, partial characterization and role in lipid transport to developing oocytes of a novel lipophorin from the cowpea weevil, Callosobruchus maculatus
Lipid transport in arthropods is achieved by highly specialized lipoproteins, which resemble those described in vertebrate blood. Here we describe purification and characterization of the lipid-apolipoprotein complex, lipophorin (Lp), from adults and larvae of the cowpea weevil Callosobruchus maculatus. We also describe the Lp-mediated lipid transfer to deve
Brazilian Journal of Medical and Biological Research. Publicado em: 17/12/2007
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32. Relevance of apolipoprotein E4 for the lipid profile of Brazilian patients with coronary artery disease
Apolipoprotein E (apoE - e2, e3, e4 alleles) plays a role in the regulation of lipid metabolism, with the e4 considered to be a risk factor for coronary artery disease (CAD). We aimed to evaluate the apoE polymorphisms in Brazilians with CAD and their influence on the lipid profile and other risk factors (hypertension, diabetes mellitus, smoking). Two hundre
Brazilian Journal of Medical and Biological Research. Publicado em: 06/01/2007
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33. Heterogeneidade e mecanismos moleculares da atividade anti-apoptótica das subfrações de HDL em células endoteliais humanas / Heterogeneity and molecular mechanisms of anti-apoptotic activity of high-density lipoprotein (HDL) subfractions on endothelial cells
Introdução: A lipoproteína de baixa densidade (LDL) e suas formas oxidadas (LDLox) possuem múltiplas propriedades aterogênicas, atuando na deposição de colesterol, indução e manutenção da inflamação, disfunção endotelial, surgimento de células espumosas na parede arterial e conseqüente formação da placa de ateroma. Adicionalmente, LDLox in
Publicado em: 2007
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34. Effect of polymorphisms of the MTHFR and APOE genes on susceptibility to diabetes and severity of diabetic retinopathy in Brazilian patients
Diabetes mellitus (DM) is a highly prevalent complex genetic disorder. There has been a worldwide effort in the identification of susceptibility genes for DM and its complications, and the 5-10-methylenetetrahydrofolate reductase (MTHFR) and apolipoprotein-E (APOE) genes have been considered good candidate susceptibility genes to this condition. The objectiv
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-07
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35. Atherogenic lipid profile of Brazilian near-term newborns
Cardiovascular disease is the primary cause of death in Brazil. Recent studies have shown that low birth weight and preterm birth are linked to a higher prevalence of cardiovascular disease. The aim of the present study was to compare the levels of lipids and apolipoproteins and atherogenic indexes between term and near-term newborn infants. A sample of umbi
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-05
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36. Risk factors, biochemical markers, and genetic polymorphisms in early coronary artery disease
OBJECTIVE: To assess the risk factors, lipid and apolipoprotein profile, hemostasis variables, and polymorphisms of the apolipoprotein AI-CIII gene in early coronary artery disease (CAD). METHODS: Case-control study with 112 patients in each group controlled by sex and age. After clinical evaluation and nutritional instruction, blood samples were collected f
Arquivos Brasileiros de Cardiologia. Publicado em: 2003-04