Antipsychotic Agents
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in an upper-middle-income country
Objective: The aim of our study was to examine the prevalence of and factors associated with antipsychotic polypharmacy (APP) among patients with serious mental illness in the current South African health care context. Methods: We collected data on patient, illness, and treatment characteristics of patients discharged on one or more antipsychotic agents fr
Rev. Bras. Psiquiatr.. Publicado em: 06/02/2017
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2. Eficácia de antipsicóticos atípicos comparados à clozapina em pacientes com esquizofrenia refratária: revisão sistemática e metanálise / Efficacy of atypical antipsychotics versus clozapine in patients with refractory schizophrenia: systematic review and meta-analysis
INTRODUÇÃO: Considera-se a clozapina como padrão-ouro para o tratamento de pacientes com esquizofrenia refratária, com base principalmente em sua eficácia comprovadamente superior em relação aos antipsicóticos típicos. No entanto, os dados acerca do uso de outros antipsicóticos atípicos ainda são escassos ou divergentes. Tendo em vista que o uso
Publicado em: 2010
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3. Perfil cognitivo, ritmo e padrÃes do sono em pacientes portadores de esquizofrenia. / Sleep alterations, circadian rhythm and cognitive function in schizophrenia â a study of 82 patients.
A esquizofrenia à uma doenÃa heterogÃnea quanto a caracterÃsticas e gravidade dos sintomas. Diversas alteraÃÃes relacionadas ao sono, com possÃveis efeitos sobre a capacidade funcional, foram descritas. Dentre os poucos estudos que registraram ritmo circadiano na esquizofrenia, alguns sugerem que os indivÃduos com alteraÃÃes de ritmo apresentam men
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/10/2007
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4. Diabetes mellitus e antipsicóticos atípicos
Pacientes esquizofrênicos têm maior risco para desenvolvimento de transtorno hiperglicêmico e o uso de antipsicóticos parece ampliar o risco de desenvolvimento de diabetes mellitus. O presente trabalho é uma revisão da literatura acerca da relação entre antipsicóticos atípicos e risco de desenvolvimento de diabetes mellitus. A pesquisa bibliográfi
Revista Brasileira de Psiquiatria. Publicado em: 2003-10
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5. In vitro chloroquine resistance modulation study on fresh isolates of Brazilian Plasmodium falciparum: intrinsic antimalarial activity of phenothiazine drugs
Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian chloroquine-resistant fresh isolates of Plasmodium falciparum. Aiming to simulate therapeutic schedules, chloroquine was employed at the concentration used for sensitive falciparum malaria treatment and anti-psycho
Memórias do Instituto Oswaldo Cruz. Publicado em: 2002-10
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6. Alcool e drogas na esquizofrenia
The aim of this investigation was to evaluate drug and alcohol use in schizophrenia through a comparative, case-control study of two groups of age and sex matched schizophrenics who fulfilled the DSMIV criteria for schizophrenia. The case group consisted of individuals with a previous history of alcohol use, at least, in the past month, and a history of drug
Publicado em: 2000
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7. Interventions for Weight Gain in Adults Treated With Novel Antipsychotics
Background: Weight gain is a significant side effect associated with typical and atypical antipsychotic agents. It has the potential to add to the increased morbidity and mortality associated with schizophrenia and schizoaffective disorder. Because the newer antipsychotic medications have proved to be superior to traditional agents in controlling the positiv
Physicians Postgraduate Press.
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8. Antipsychotic Drugs and Dopamine-Stimulated Adenylate Cyclase Prepared from Corpus Striatum of Rat Brain
Antipsychotic drugs and their clinically impotent congeners were examined as inhibitors of dopamine-sensitive adenylate cyclase (EC 4.6.1.1) in cell-free membrane preparations of the caudate-putamen of rat brain. Of 12 neuroleptic drugs with reported antipsychotic efficacy, all inhibit stimulation of adenylate cyclase by 40 μM dopamine at micromolar concent
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9. Atypical Antipsychotic Use in the Treatment of Psychosis in Primary Care
Atypical antipsychotics are a class of novel agents increasingly employed for the treatment of psychotic disorders. The pharmacodynamic properties of the atypicals appear to impact a broader spectrum of psychotic symptoms than had been appreciated with older generation antipsychotics. In addition, the atypical agents appear to have a reduced risk of neurolog
Physicians Postgraduate Press.
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10. Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs
Adenylate cyclase (EC 4.6.1.1), selectively stimulated by low concentrations of dopamine, has been found in the olfactory tubercle, the nucleus accumbens, and the caudate nucleus of several mammalian species. Several different classes of drugs effective in the treatment of schizophrenia (antipsychotic drugs) were potent inhibitors of the stimulation by dopam
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11. Metabolic Issues With Atypical Antipsychotics in Primary Care: Dispelling the Myths
Background: Recently, much attention has been focused on the increased rate of metabolic syndrome componen ts among psychiatric patients, including glucose intolerance, hyperglycemia, diabetes mellitus, hyperlipidemia, hypertension, and weight gain. Various reports have identified cases of newly diagnosed diabetes during treatment with atypical antipsychoti
Physicians Postgraduate Press.
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12. Recognizing and Managing Antipsychotic Drug Treatment Side Effects in the Elderly
Although atypical antipsychotics differ from conventional antipsychotics in their decreased ability to cause reversible drug-induced movement disorders/motor side effects such as dystonia, drug-induced parkinsonism, and akathisia and potentially persistent drug-induced movement disorders/motor side effects such as tardive dyskinesia, no antipsychotic agent c
Physicians Postgraduate Press.