Antimony N Methylglucamine
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Epidemiological aspects of American cutaneous leishmaniasis (ACL) in an endemic area of forest extractivist culture in western Brazilian Amazonia
ABSTRACT The study sought to analyze clinical and epidemiological aspects of cutaneous leishmaniasis (CL) in Xapuri, Acre, Brazil. Data from 2008 to 2014 registered in the notification records of the disease of the Information System of the Complaints of Notification (SINAN), and the data of the Information Department of the Unified Health System (DATASUS) a
Rev. Inst. Med. trop. S. Paulo. Publicado em: 13/04/2017
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2. Efficacy and safety of low-dose pentavalent antimonial for treatment of cutaneous leishmaniasis by Leishmania (Viannia) braziliensis in Bahia, Brazil: a randomized clinical trial / Eficácia e segurança da dose baixa de antimonial pentavalente no tratamento da leishmaniose cutânea por Leishmania (Viannia) braziliensis em área endêmica da Bahia, Brasil : ensaio clínico randomizado
A randomized open-label clinical trial was conducted to assess the efficacy and safety of an intravenous dose of 5 mg/kg/day antimony-N-methyl-glucamine for 20 days compared with the conventional dose of 15mg/kg/day for 20 days for treatment of cutaneous leishmaniasis (CL) associated with L. (V.) braziliensis infection. This trial was registered with clinica
Publicado em: 2009
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3. 2-substituted quinoline alkaloids as potential antileishmanial drugs.
Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp. BALB/c mice infected with Leishmania amazonensis PH8 or H-142 or Leishmania venezuelensis were treated 1 day after the parasitic infection with a quinol
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4. In vivo efficacy of oral and intralesional administration of 2-substituted quinolines in experimental treatment of new world cutaneous leishmaniasis caused by Leishmania amazonensis.
The antileishmanial efficacies of 2-n-propylquinoline, chimanines B and D, 2-n-pentylquinoline, 2-phenylquinoline, 2-(3,4-methylenedioxyphenylethyl) quinoline, and two total alkaloidal extracts of Galipea longiflora were evaluated in BALB/c mice infected with Leishmania amazonensis or Leishmania venezuelensis. Animals were treated for 4 to 6 weeks postinfect