Antimicrobial And Toxicity Activity
Mostrando 1-12 de 101 artigos, teses e dissertações.
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1. ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS
In recent years, there has been an increasing interest in the development of antimicrobial materials for different applications, especially in the biomedical field. In this context, chitosan is one of the most employed materials due to its highly attractive properties, such as biocompatibility, biodegradability, non-toxicity, and antimicrobial activity again
Química Nova. Publicado em: 2022
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2. Characterization of Commercially Available Turmeric for Use in Pharmaceutical Products and Food Supplements
We addressed some physicochemical and biological differences in commercial turmeric, acquired from both handling pharmacies and stores selling natural products for quality assessment. For this, it was determined the melting point, antioxidant activity by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH), antimicrobial activity via the agar disk-diffusion assay,
Journal of the Brazilian Chemical Society. Publicado em: 2022
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3. CONSTITUENTS FROM ROOTS OF Maytenus distichophylla, ANTIMICROBIAL ACTIVITY AND TOXICITY FOR CELLS AND Caenorhabditis elegans
Maytenus distichophylla is a medicinal species used in Northeast of Brazil. The hexane (HE), chloroform (CE), ethyl acetate (EAE) and methanol (ME) extracts and compounds from its roots were evaluated for their protective activity against Staphylococcus aureus and Candida albicans. The cytotoxicity for chronic myeloid leukemia (K562), acute monocytic leukemi
Quím. Nova. Publicado em: 2020-09
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4. SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NEW Cu (II), Co (II) AND Sn (II) COMPLEXES WITH THE SODIUM HYDROTRIS(2-MERCAPTOTHIAZOLYL)BORATE LIGAND
The emergence of antibiotic resistance among microbial pathogens is a serious public health problem, resulting in a constant need of discovering new antibiotics. For this purpose, we synthetized and determined the antimicrobial activity of copper (Cu), cobalt (Co), and tin (Sn) complexes coordinated with scorpionate ligand in a tridentate mode against microo
Quím. Nova. Publicado em: 2020-05
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5. Brazilian stingless bee propolis and geopropolis: promising sources of biologically active compounds
ABSTRACT Stingless bee products such as honey, pollen, propolis, and geopropolis have been used for centuries in traditional medicine for the treatment of several illnesses. Investigation of the biological activity of stingless bee products, especially propolis and geopropolis, has revealed promising therapeutic properties. About 20% of total Neotropical sti
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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6. Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity; physicochemical properties, in vitro release and oral acute toxicity
Inorganic and carbon based nanomaterials are widely used against several diseases, such as cancer, autoimmune diseases as well as fungi and bacteria colonization. In this work, Santa Barbara Amorphous mesoporous silica (SBA), Halloysite Nanotubes (HNTs) and Multiwalled Carbon Nanotubes (CNTs) were loaded with fluoroquinolone Levofloxacin (LVF) to be applied
Braz. J. Pharm. Sci.. Publicado em: 12/08/2019
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7. IMPLICAÇÕES DE EXTRATO DE Erythrina crista-galli COMO ANSIOLÍTICO PARA Carassius auratus
Resumo A fitoterapia vem sendo utilizada em criação de peixes a fim de promover estabilidade no ambiente de cultivo e na profilaxia de doenças, contribuindo para a melhoria do bem-estar animal. Dentre os fitoterápicos, Erythrina crista-galli tem efeito sedativo e atividade antioxidante e antimicrobiana, além de funcionar como calmante natural. Na ausên
Ciênc. anim. bras.. Publicado em: 10/06/2019
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8. NANOTOXICOLOGIA DE NANOPARTÍCULAS DE PRATA: TOXICIDADE EM ANIMAIS E HUMANOS
Silver nanoparticles (AgNPs) have important antimicrobial activity. These nanoparticles are present in several commercial products, leading to human and environmental exposure. This review presents a critical view of the toxic effects of Ag NPs on in vitro and in vivo biological models. It is noteworthy that the toxicity of AgNPs is dependent on several para
Quím. Nova. Publicado em: 2019-02
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9. Synergistic antibacterial effect of statins with the complex {[1-(4-bromophenyl)-3-phenyltriazene N 3 -oxide-κ 2 N 1 ,O 4 ](dimethylbenzylamine-κ 2 C 1 ,N 4 )palladium(II)}
Abstract The treatment of infections caused by resistant microorganisms represents a big challenge in healthcare due to limited treatment options. For this reason, the discovery of new active substances which are able to perform innovative and selective actions is of great impact nowadays. Statins and triazenes (TZC) have consolidated as a promising class of
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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10. In vitro susceptibility of methicillin-resistant Staphylococcus aureus isolates from skin and soft tissue infections to vancomycin, daptomycin, linezolid and tedizolid
Abstract Introduction Treatment of multidrug-resistant Gram-positive infections caused by Staphylococcus aureus remains as a clinical challenge due to emergence of new resistance mechanisms. Tedizolid is a next-generation oxazolidinone, recently approved for skin and soft tissues infections. We conducted a study to determine in vitro susceptibility to vanco
Braz J Infect Dis. Publicado em: 2017-10
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11. Synthesis and evaluation of arylamidine derivatives for new antimicrobial and cytotoxic activities
ABSTRACT A series of arylamidines 3a-j was designed, synthesized and investigated for antimicrobial activity. Structures of the compounds were confirmed by IR, 1H-NMR and 13C-NMR and a 2D spectroscopic study was performed. A preliminary screening of the antimicrobial tests clearly showed that three out of ten arylamidines, viz, 3f, 3g and 3i, were effective
An. Acad. Bras. Ciênc.. Publicado em: 2017-06
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12. Evaluation of cytogenotoxicity, antioxidant and hypoglycemiant activities of isolate compounds from Mansoa hirsuta D.C. (Bignoniaceae)
ABSTRACT Mansoa hirsuta (Bignoniaceae) is a native plant from caatinga in Brazilian semiarid. This plant has been locally used as antimicrobial and hypoglycemiant agents, but their action mechanisms and toxicity remain largely unknown. Therefore, we evaluated the composition and antioxidant, cytoprotective and hypoglycemiant effects of raw extract, fractions
An. Acad. Bras. Ciênc.. Publicado em: 2017-03