Antigenic Characterization
Mostrando 1-12 de 613 artigos, teses e dissertações.
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1. Protein PEGylation for the design of biobetters: from reaction to purification processes
The covalent attachment of polyethylene glycol (PEG) to therapeutical proteins is an important route to develop biobetters for biomedical, biotech and pharmaceutical industries. PEG conjugation can shield antigenic epitopes of the protein, reduce degradation by proteolytic enzymes, enhance long-term stability and maintain or even improve pharmacokinetic and
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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2. Detection and genetic characterization of Mamastrovirus 5 from Brazilian dogs
Abstract Mamastrovirus 5 (MAstV5), belonging to the Astroviridae (AstV) family, previously known as canine astrovirus or astrovirus-like particles, has been reported in several countries to be associated with viral enteric disease in dogs since the 1980s. Astroviruses have been detected in fecal samples from a wide variety of mammals and birds that are assoc
Braz. J. Microbiol.. Publicado em: 2018-09
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3. Virulence genes and genetic relationship of L. monocytogenes isolated from human and food sources in Brazil
ABSTRACT The herein presented assay provided a bacteriological and molecular characterization of 100 samples of L. monocytogenes isolated from human (43) and food (57) sources, from several regions of Brazil, and collected between 1975 and 2013. Antigenic characterization defined 49% of serotype 4b samples, followed by 28% of serotype 1/2b, 14% of serotype 1
Braz J Infect Dis. Publicado em: 2017-06
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4. Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis
Abstract: Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease, problems related to the development of parasite resistance and side effects associated with the compounds used have been noted. Hence, alternative approaches for VL control are desirable. Some metho
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-08
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5. Purification and characterization of a hyaluronidase from venom of the spider Vitalius dubius (Araneae, Theraphosidae)
BackgroundVenom hyaluronidase (Hyase) contributes to the diffusion of venom from the inoculation site. In this work, we purified and characterized Hyase from the venom of Vitalius dubius (Araneae, Theraphosidae), a large theraphosid found in southeastern Brazil. Venom obtained by electrical stimulation of adult male and female V. dubius was initially fractio
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 04/02/2014
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6. CARACTERIZAÇÃO GENÉTICA E ANTIGÊNICA DE ISOLADOS BRASILEIROS DO VÍRUS DA DIARRÉIA VIRAL BOVINA / GENETIC AND ANTIGENIC CHARACTERIZATION OF BRAZILIAN ISOLATES OF BOVINE VIRAL DIARRHEA VIRUS ISOLATES
Amostras de campo do vírus da diarréia viral bovina (BVDV) apresentam diferenças genéticas e antigênicas que podem influenciar no diagnóstico e na produção de vacinas. Os objetivos do presente trabalho foram selecionar e caracterizar isolados de BVDV para potencial uso em testes de diagnóstico e vacinas, e caracterizar genética e antigenicamente am
Publicado em: 2011
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7. Caracterização antigênica do Trypanosoma evansi usando soros de bovinos, equinos, cães e quatis experimentalmente e naturalmente infectados
O trabalho de pesquisa investigou a presença de anticorpos anti- T. evansi em animais da sub-região da Nhecolândia, no Pantanal sul-mato-grossense, pelo ensaio imunoenzimático (ELISA) e a reação de imunofluorescência indireta (RIFI). O reconhecimento de polipeptídeos de T. evansi foi realizado pela técnica de "Western blotting", utilizando soros de
Revista Brasileira de Parasitologia Veterinária. Publicado em: 2010-06
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8. A preliminary survey of M. hyopneumoniae virulence factors based on comparative genomic analysis
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (PEP), a major problem for the pig industry. The mechanisms of M. hyopneumoniae pathogenicity allow to predict the existence of several classes of virulence factors, whose study has been essentially restricted to the characterization of adhesion-related and major antigenic protei
Publicado em: 2010
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9. Caracterização molecular de rotavírus genotipo P[6] de origem humana em um foco de diarreia neonatal suína
Neonatal diarrhea is the major piglet health problem in swine production systems worldwide.In intensive production the porcine serogroup A rotaviruses (PoRV-A) are common cause of diarrhea in suckling and recently weaned piglets. The VP4 and VP7 proteins of the outer layer viral capsid of RV-A are relevant for immunity against rotavirus infection by inducing
Publicado em: 2010
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10. CaracterizaÃÃo molecular dos vÃrus sincicial respiratÃrio humano circulantes em Fortaleza-Cearà durante cinco perÃodos epidÃmicos consecutivos (2004-2008). / Molecular characterization of human repiratÃrio syncytial virus circulating in Fortaleza, Ceara during five consecutive epidemic periods (2004-2008).
vÃrus sincicial respiratÃrio humano (VSRh) à o agente viral mais freqÃentemente relacionado a infecÃÃes do trato respiratÃrio inferior em crianÃas menores de dois anos de idade. O VSRh à caracterizado antigenicamente em dois grupos: A e B, e cada grupo apresenta vÃrios subgrupos. A glicoproteÃna G à a principal responsÃvel pela a variaÃÃo anti
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2009
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11. Caracterização de marcadores de virulência em Paracoccidioides brasiliensis. / Characterization of markers of virulence in Paracoccidioides brasiliensis.
Paracoccidioidomycosis (PCM) is a human systemic granulomatous disease, prevalent in South America, caused by a thermodimorphic fungus, Paracoccidioides brasiliensis. This fungus presents complex antigenic structure and some of these components have been related with its pathogenicity, of which little is known. The virulence recovery of isolates by passage i
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/06/2009
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12. The epidemiology and antigenic characterization of influenza viruses isolated in Curitiba, South Brazil
Several studies conducted all over the world have reported that the influenza virus is associated with great morbidity and mortality rates. In this study, we analyzed the incidence of the influenza virus between 2000 and 2003 in Curitiba. We studied 1621 samples obtained from outpatients and hospitalized patients of both sexes and all ages. The study was con
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-03