Antigen Presenting Cell
Mostrando 13-24 de 704 artigos, teses e dissertações.
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13. An in vitro model for dengue virus infection that exhibits human monocyte infection, multiple cytokine production and dexamethasone immunomodulation
An important cytokine role in dengue fever pathogenesis has been described. These molecules can be associated with haemorrhagic manifestations, coagulation disorders, hypotension and shock, all symptoms implicated in vascular permeability and disease worsening conditions. Several immunological diseases have been treated by cytokine modulation and dexamethaso
Memórias do Instituto Oswaldo Cruz. Publicado em: 2007-12
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14. Low expression of antigen-presenting and costimulatory molecules by lung cells from tuberculosis patients
Costimulatory and antigen-presenting molecules are essential to the initiation of T cell immunity to mycobacteria. The present study analyzed by immunocytochemistry, using monoclonal antibodies and alkaline phosphatase-anti-alkaline phosphatase method, the frequency of costimulatory (CD86, CD40, CD40L, CD28, and CD152) and antigen-presenting (MHC class II an
Brazilian Journal of Medical and Biological Research. Publicado em: 29/10/2007
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15. Células de doadores normais primadas in vitro respondem ao antígeno ovular solúvel e ao peptídeo sintético MAP4 derivado da triose fosfato isomerase do Schistosoma mansoni. / Cells of normal primed givers in vitro answer to the antigen to ovular soluble and synthetic peptíde MAP4 derived from triose-phosphate isomerase of the Schistosoma mansoni.
It has been well established that Schistosoma mansoni induces an initial CD4+ T-cell response. The early events in the immune response to schistosomiasis have been evaluated in mice but few studies have focused on the early response in humans, especially in regard to parasite antigens that are potential vaccine candidates. To study the early immune response
Publicado em: 2007
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16. Avaliação da Imunogenicidade de Dois Novos Imunobiológicos Candidatos a Vacina Contra Leishmaniose Visceral Canina
Considering the importance of immunoprophylactic strategies for the control of visceral leishmaniasis, and the lack of studies concerning the cellular and humoral events that occur during vaccination in dogs, we have attempted to evaluate the immune response of a promising new vaccines candidate against canine visceral leishmaniasis (CVL). Thirty five mongre
Publicado em: 2007
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17. "O efeito da ciclosporina A na população de células apresentadoras de antígenos em hiperplasia gengival medicamentosa" / The effect of antigen-presenting cells in the human gingival overgrowth
A proposta do nosso estudo foi comparar o número de células apresentadoras de antígenos (CAAs) presentes em biópsias de gengivite (G) e de hiperplasia gengival induzida por ciclosporina (HGIC). Vinte e oito biópsias de pacientes com G e 14 biópsias de HGIC foram analisadas no epitélio de revestimento bucal (ERB), epitélio sulcular (ES) e no tecido co
Publicado em: 2006
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18. Avaliação da espressão de glicoproteinas potencialmente especificas na membrana plasmatica de celulas Natural Killer uterinas de camundogos / Evaluation of expression of potentially specific glycoproteins in plasmatic membrane of mouse uterine Natural Killer
The phenomenon of pregnancy in mammalians with hemochorial type placenta ions where the allogeneic fetus presenting the half of gene from paternal origins growth in tight contact with maternal tissues, without triggering the rejections responses of maternal immune system is still a non-solved question of immunology of reproduction. The cross-talk at maternal
Publicado em: 2006
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19. Estudo da influência da infecção por Leishmania Chagasi e do impacto da terapêutica específica eficaz no perfil da resposta imune celular de indivíduos portadores de Leishmaniose Visceral / Study of influence of the Leishmania Chagasi infection and the therapeutical specific efficient of the impact in the cell immune reponse in carriers patients Leishmaniose visceral
We evaluated the cellular immunity profile associated with the infection for Leishmania chagasi and with the cure of Visceral Leishmaniasis (VL) after specific chemotherapy, by studying the plasmatic cytokine profile, nitric oxide (NO) levels and intracellular cytokine expression in the absence of stimuli as well as after short-term in vitro stimulation with
Publicado em: 2006
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20. Prostanoids modulate inflammation and alloimmune responses during graft rejection
Acute rejection of a transplanted organ is characterized by intense inflammation within the graft. Yet, for many years transplant researchers have overlooked the role of classic mediators of inflammation such as prostaglandins and thromboxane (prostanoids) in alloimmune responses. It has been demonstrated that local production of prostanoids within the allog
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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21. Painel racionalizado de anticorpos monoclonais para leucemias agudas : seu valor diagnostico e prognostico
Acute leukemia is characterized by a c1onal proliferation of haematopoietic stem cell substituting the normal bone marrow. The recent WHO c1assification for acute leukemia separates entities by recurrent cytogenetic abnormalities and immunophenotypic features presenting prognostic impact. We have examined the distribution and impact on survival of the expres
Publicado em: 2005
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22. Immunity and immunosuppression in experimental visceral leishmaniasis
Leishmaniasis is a disease caused by protozoa of the genus Leishmania, and visceral leishmaniasis is a form in which the inner organs are affected. Since knowledge about immunity in experimental visceral leishmaniasis is poor, we present here a review on immunity and immunosuppression in experimental visceral leishmaniasis in mouse and hamster models. We sho
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-04
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23. Evolução clinica da encefalomielite experimental auto-imune em camundongos geneticamente modificados (knockout) para a oxido nitrico sintase induzida
Multiple sclerosis (MS) is the most common human demyelinating disease of the central nervous system (CNS). Based on the fact that it shares similarities in relation to course of the disease and histology, Experimental auto-immune encephalomyelitis (EAE) has been used extensively as an animal model for MS. EAE is a Thl cell-mediated autoimmune disease induce
Publicado em: 2004
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24. Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes?
Despite extensive genetic and immunological research, the complex etiology and pathogenesis of type I diabetes remains unresolved. During the last few years, our attention has been focused on factors such as abnormalities of islet function and/or microenvironment, that could interact with immune partners in the spontaneous model of the disease, the non-obese
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-04